Impregnating gauze



Patented May 16, 1944 NT OFFICE IMPBEGNATING auze Woliie Barry Felnstone,

or to American y Stamford, Conn, assignanamiii Company. New Fork,

N. Y., a corporation of Maine No Drawing.

'3 Claims.

This invention relates to the impresnationof gauze and ismore particularly concerned with including sulfadiazine in such impresnation treatment.

Hospital gauze for use in operations and the s customary hospital technique and there is then like is usually prepared by impregnating the addeda suitable amount of the emulsion A gauze with petroleum jelly and sterilizing the cover is then placed on the container and the gauze so prepared. This operation is usually whole is put into an autoclave where it is subcarried out by placing layers of the gauze in a .lected to a pressure of about 15 pounds of steam suitable metal container, adding petroleum Jelly for minutes. The box and its contents are thereto and placing the entire container in an completely sterilized and the emulsion will be autoclave where it is subjected to about 15 f und h v n dispersed u if y r shpounds pressure of steam for bout 15 minut out-all of the layers of the gauze so that each This brings about sterilization of the gauze and lay r f. auz ontains substantially the same at the same time melts t petroleum l 1 15 amount of petroleum Jelly and sulfadiazine. pregnates the gauze and makes it suitable for To facilitate impregnation of the gau ei i operations and t l sometimes preferred to wet the gauze with a s m m has been used in an Increasing dilute solution of a wetting agent and to wring amount in post-operative procedure. However, out a y excess solution p io P acing the such use has been attended with some incon- B e n the metal eontelner end pri r to the venience due to the necessity of separate hana i i n of the emulsion- In e alternative. the clling and the like. It would be desirable to mix Wetting agent y be Incorporated Into the mulsulfadiazine with the petroleum Jelly used to' sion 80 s as su h a nt s of a t pe as will not impregnate the gauze as described above but break down the emulsion As ill trat v th since the sulfadiazine is not soluble in the pesuitable wetting agent may e selected from troleum Jelly, mixtures thereof separate into their one or more of he following types: diamyl, several t t t and uniform lmpregnaflon dihexyi or dioctyl sulfosuccinic esters and salts of the several layers of the gauze would not be tholoillfo! olkyleted naphthalene sulfonic bt acids, long chain quaternary ammonium com- I have now. found that I may impregnate the, o i sulfonflted filllfeted er -lcoholsr hospital gauze during the sterilization operation lauryl sulfate, the salts of e s a or with a mixture of sulfadiazine with petroleum o doh r a coh s. ulf nated oi s. or the jelly o lanolin i guidance t the usual mineral or vegetable ty aromatic sulfonates. practice if the mixture is used in the form ofa 4 etc. g i s t b emulsion, This serves to impregnate 35 The method of preparation of the emulsion the gauze with the petroleum jelly or the lanolin may be varied considerably wi o t affectin the as in the past and, at th same time distributes results to any great extent- By va ying the th sulfadlazlne unlfomly throughout the mass amount ofwater in the emulsion, the consistf gauze, ency thereof is correspondingly changed a1- Moi-c specifically the following is descriptive of though for most purposes a n Paste sultone form of my invention which is not limited We In place of Petroleum lelly, I m to the specific t l t f 5 quantitie use lanolin which, for the same ratio of ingrethroughout are by weight unless otherwise spei gives 8 correspondingly h a ier l e-Ste. cifi'ed. Other substances may be added to the mixtures A mixture is made of the following: Prepaflng the emulsions so long as they do i not interfere with the action of the sulfadiazine Parts and the petroleum Jelly or lanolin. Thusthe Petroleum jelly 54 ddition of V4 of 1% allantoin to the mixture sulfadiazine 5 has been found to serve a useful purpose. 'rriethanolamine 2 The emulsions utilized in the present invention Stearic acid 4 are Stable for long. periods of time and do not a Water 35 spoil or discolor even upon being exposed to the This mixture is converted into an emulsion by Application September o, i941. Serial No.

(0!. lei-s4) the use of a suitable stirring device and 110- 55 mogeniaer to produce a homogeneous and stable. thin paste.

In the use of this emulsion.

of gauze are placed in a metal a number of layers container as is the air. -They serve formly with the petrole'um'ielly or lanolin and at the same timepermita uniform distribution to impregnate the gauge uniotthesniisdhslmthmughouttheseverallayers oi'gametnated 'iheaeemuisionsareusedin exactly the same manner as has been done prerionslyrlththepetroieum'ieily and require It will be obvious that many modifications and variations in the processes and compositions described in my invention may be made without departing from the spirit and scope of the invention as dei'lned in the appended claims.

Iclaim:

tion of a wetting agentand heating the "we in contact with an aqueous emulsion containing dispersed suliadiasine and a greasy substance aslasted from the group consisting oipetroleum jelly and lanolin. the heating being carried out at a temperature and for a time suiiicient to sterilize the gauze and to melt the greasy substance s0 that it is dispersed substantially unis 1. The proeesss of treating gauze which com- I prises heating the gauze in contact with an aqueous emulsion containing dispersed sulfadiasine and a greasy substance selected from the group consisting of petroleum jelly and lanolin,

the heating being carried out at a temperature and for a time suflicient to sterilize the gauze and to melt the greasy substance so that it is dispersed substantially uniformly throughout the gauze, together with the sulfadiazine.

2. The process of treating gauze which comprises moistening the gauze with a dilute soluiormly throughout the gauze, together with the suli'adlazlne. a

3. The process oi. treating gauze which comprises heating the gauze in contact with an aqueous emulsion containing dispersed sultadiazine, triethanolamine stearate and a greasy wom's naartYr'emsrom-z. 

